Winfrey suggests that young people should not be discouraged from working an internship or job that isn't perfect in every way. "Your job is not who you are, it's just what you're doing on the way to who you will become."

This article first appeared on CNBC.com

The desire for fulfilling work is a defining characteristic of Millennials and Generation Z. Cathy Engelbert, CEO of Deloitte — which has a nearly 62 percent millennial workforce — recently told CNBC, "They're all looking for purpose-driven, civic-minded, socially responsible companies."

Despite this trend, Winfrey insisted that young people should not be discouraged from working a job that isn't perfect in every way. "Your job is not who you are, it's just what you're doing on the way to who you will become."

This lesson may even provide some relief to young people and recent graduates who feel the collective cultural pressure to be working a job that meets all of their aspirations, when in fact, most people do not graduate from college and immediately start their dream job.

For those young people who have a job, if not their dream job, Winfrey's advice was to learn, make the most of it and demonstrate undeniable talent.

"Every remedial chore, every boss who takes credit for your ideas — that is going to happen — look for the lessons because the lessons are always there," she said. "And the number one lesson I can offer you where your work is concerned is this: Become so skilled, so vigilant, so flat-out fantastic at what you do that your talent cannot be dismissed."